Bifidobacterium bifidum

Bifidobacterium bifidum occurs naturally in the human gut microbiome, is commonly used as a probiotic, and may provide a variety of benefits, including aiding vitamin K and B-complex vitamins production within the intestines, which are essential to human function.

Supplementing the diet with B. bifidum has been shown to improve digestion and boost immune function. B. bifidum promotes microbiota equilibrium and optimal digestion, creating an unfavorable environment for the production of histamine, a chemical responsible for triggering allergic reactions. In addition, B. bifidum may enhance the body's natural antibody immune response. These conclusions may indicate that B. bifidum can help fight intestinal pathogens, digestive irregularities, and histamine production, ultimately improving the body's immunity and reducing risk of allergic reactions.

One study revealed short-term supplementation with B. bifidum may result in restoration of balanced gastrointestinal (GI) tract microflora. In addition, notable improvements in alcohol-induced liver injury were seen with B. bifidum when compared to standard therapy alone.

Probiotics like B. bifidum can be particularly effective in diarrheal treatment, including infectious diarrhea and antibiotic associated diarrhea. Rebalancing the GI tract microflora with probiotic supplements can result in a decrease in stool frequency, fecal weight, and abdominal cramps.


C. Picard, J. Fioramonti, A. Francois et al. Review article: bifidobacteria as probiotic agents – physiological effects and clinical benefits. Alimentary Pharmacology and Therapeutics. 2005. 22 (6): 495-512.doi: 10.1111/j.1365-2036.2005.02615.x

Chitapanarux, I., Chitapanarux, T., Traisathit, P. et al. Randomized controlled trial of live lactobacillus acidophilus plus bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients. Radiation Oncology. 2010. 5(31). doi: 10.1186/1748-717X-5-31

Irina A. Kirpich, Natalia V. Solovieva, Svetlana N. Leikhter et al. Probiotics restore bowel flora and improve liver enzymes in human alcohol-induced liver-injury: a pilot study. Alcohol an International Biomedical Journal. 2008. 42(8): 675-682. doi: 10.1016/j.alcohol.2008.08.006

Michael de Vrese, Winkler, P., Rautenberg, P. et al. Effect of Lactobacillus gasseri PA 16/8, Bifidobacterium longum SP 07/3, B. bifidum MF 20/5 on common cold episodes: a double blind, randomized, controlled trial. Clinical Nutrition. 24 (4). Aug 2005: 481–91. doi: 10.1016/j.clnu.2005.02.006