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Oral Probiotics

Oral Probiotics

Your mouth is your body’s first line of defense, providing easy access for many infections, especially when your oral microbiome is compromised by diet, daily use of mouthwash, flossing, or even vigorous brushing. Your microbiome can quickly shift and create painful issues, but with our oral probiotics, your oral microbiome stays balanced and at its healthiest.

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How Can Oral Probiotics Help Me?

Dental Probiotics

You likely know that the microbes living in your intestines affect your general health, but it might surprise you that both good and bad bacterial strains colonize your mouth, too. Your mouth provides easy access for many infections, especially when your balance of healthy oral bacteria is compromised by poor diet, daily use of mouthwash, flossing, or even brushing your teeth with products that contain fluoride too often. Your microbiome can quickly shift and create painful oral issues. Our oral probiotics help you maintain your oral microbiome and encourage optimal health.

We've included two well-studied Bacteriocin-Like-Inhibitory Substances (BLIS), probiotics targeted for oral health, Streptococcus salivarius M18 and S. salivarius K12, in our oral health probiotics. S. salivarius K12 maintains ear, nose, throat (ENT) and immune health while S. salivarius M18 maintains dental and gum health. Both S. salivarius M18 and S. salivarius K12 crowd out bad bacteria in the oral cavity, encouraging good bacteria to grow.

Many oral health products only treat symptoms like bad breath temporarily. When BLIS K12® and BLIS M18™ grow in your mouth, they allow good bacteria to repopulate, helping to eliminate bad bacteria and target bad breath.

A healthy oral microbiome that has strong colonies of beneficial bacteria may help prevent infections. The nine unique strains in our oral probiotic are targeted to rebalance your oral microbiome and help you maintain optimal oral health.

What is inside each pill

9 Targeted Probiotic Strains, including Lactobacillus and Streptococcus to effectively counteract the indiscriminate effects of mouthwash, diet, and other lifestyle choices that can potentially compromise your oral microbiome and lead to dysbiosis. BLIS K12™ and BLIS M18™ are advanced and targeted probiotics for oral cavity and upper respiratory tract health. They are proprietary strains of S. salivarius, which naturally help support fresh breath and immune system health. Specific strains include L. plantarum, L. reuteri, L. paracasei, L. casei, S. salivarius BLIS K12, S. salivarius BLIS M18, L. salivarius, S. thermophilus, and L. acidophilus.

3 Billion Colony Forming Units† per chewable.  Since oral probiotic strains don’t need to survive the harsh environment of your intestines, they are able to colonize more easily than digestive probiotics. These strains live in your mouth on the tongue, tonsils, and within the ear, nose and throat (ENT), so chewing them is the most efficient delivery method.

All Natural. At Biome360, we don’t rely on additives. In addition, we do not include bacteria or yeasts that cannot naturally be found in the human gut, like Soil Based Organisms (SBOs).

Other Ingredients are Isomalt, Inulin, Microcrystalline Cellulose, Glyceryl Behenate, Dicalcium Phosphate, Spearment Flavor (natural) and Stevia.

  • Gluten Free
  • Lactose Free
  • No Artificial Colors
  • No Artificial Flavors
  • No Chemicals
  • No Eggs
  • No Iron
  • No Nuts
  • No Preservatives
  • No Soy
  • No Sugar
  • Non-GMO
  • Vegetarian
  • Wheat Free
  • Yeast Free

How does it work?


Both BLIS (Bacteriocin-Like Inhibitory Substances) probiotic strains start to work in the mouth: K12 supports ear, nose, throat and immune health while BLIS M18 primarily supports dental health.

Our oral probiotic is uniquely formulated with the most effective and clinically proven oral probiotic strains to repopulate your oral cavity, helping to break up plaque, reduce oral health challenges such as cavities, teeth-staining, thrush, gingivitis, tonsil stones, canker sores, and prevent ear, nose, and throat infections.

BLIS K12 enters the mouth and attaches to cells in the oral cavity. Once colonized, BLIS K12 crowds out the bad bacteria, keeping them from adhering to the host. Many pathogens are susceptible to the BLIS molecules Salivaricins A and B, including the bacteria that cause bad breath, sore throats, and respiratory tract and ear infections.

M18 has unique abilities that allow it to break up plaque and neutralize acid that can be harmful to teeth and gums. S. mutans, one of the many organisms responsible for dental plaque, produce lactic acid, which degrades tooth enamel and dentine, ultimately leading to cavities and possibly tooth loss. Research has shown that BLIS M18 produces an enzyme known as urease, which neutralizes acid in the oral cavity.

While S. mutans produce lactic acid, they also produce extracellular polysaccharides, which contribute to the plaque biofilm, allowing problematic bacteria to come in close contact with gum tissue. Limited numbers of S. salivarius strains, including BLIS M18, produce an enzyme called dextranase, which helps break down plaque biofilms caused by S. mutans.

† At time of manufacture. Equivalent to 1 Billion CFU at expiration.

    BIO-tract® and LiveBac® are registered trademarks of Nutraceutix.

      BLIS K12® and BLIS M18™ are trademarks of BLIS Technologies Limited.